Dr. Yang Yun


Dr. Daniel B. Sheffer
Dr. Yang Yun
 

Dr. Yang Yun
Assistant Professor

Phone: 330-972-6619
Fax: 330.374.8834
Office:  
E-mail:

yy@uakron.edu



  Education
Ph.D. in Engineering with Concentration in Biomedical Engineering, University of Memphis,1999
M.S. in Biomedical Engineering, University of Memphis, 1994
B.S. in Mechanical Engineering, Christian Brother University, 1989

  Experience
Assistant Professor, Department of Biomedical Engineering. The University of Akron, 2004 - present
Postdoctoral Fellow, Department of Biomedical Engineering. State University of New York at Stony Brook, 2000 - 2004
Instructor and Adjunct Professor, Department of Natural Sciences and Mathematics, Crichton College, 1997-1998

  Courses Taught
4800:485:001&3 and 4800:697:001: Advance Biomaterials and Laboratory
4800:697:003: Advances in Gene and Drug Therapy Delivery Systems
4800:697:001: Research Techniques for Biomaterials and Tissue Engineering

  Research Intrests

  1. Biomaterial Development and Characterization
  2. Nonviral Gene Therapy
  3. Drug Delivery
  4. Tissue Engineering
  5. Nanotechnology
  6. Cardiovascular Dynamics and Mechanics


  Patents
W. Chen, G. R. Gaudette, H. Jiang, A. S. Saltman, and Y. H. Yun, “Biodegradable Polymer Device,” US provisional patent application number 10/364,877.

  Recent Publications
E. U. Azeloglu*, Y. H. Yun,* A. E. Saltman, I. B. Krukenkamp, F. Chiang, and W. Chen, and G. R. Gaudette “A technique for evaluating regional mechanical function in multiple sites in the intact porcine heart,” Journal of Biomechanics, (Accepted, *Made equal contributions to this manuscript).

A. Kim, P. Yellen, Y. H. Yun, E. U. Azeloglu, and W. Chen, “Delivery of a hyaluronan synthase gene via a crosslinked hyaluronan film,” Biomaterials, vol. 26 (13), p. 1585-1593, (2005).

Y. H. Yun and W. Chen, “Microspheres formulated from native hyaluronan for applications in gene therapy,” Polymeric Gene Delivery: Principles and Applications, M. M. Amiji (ed.) Boca Raton: CRC Press LLC, p. 475-486, 2004.

Y. H. Yun, D. J. Goetz, P. Yellen, and W. Chen, “Hyaluronan microspheres for sustained gene delivery and site specific targeting,” Biomaterials, vol. 25 (1), p. 147-157, (2004).

Y. H. Yun, A. Kim, and W. Chen, “The application of derivatized hyaluronan for non-viral gene therapy,” Hyaluronan, E. A. Balazs and V. C. Hascall (eds.) Cambridge: Woodhead Publishing LTD, (In press).

Y. H. Yun, R. Chan, H. Liang, and W. Chen, “Sustained release of polyplexes and DNA from biodegradable microspheres composed of PEG grafted chitosan and PLGA,” (In preparation).

E. U. Azeloglu, Y. H. Yun, A. E. Saltman, I. B. Krukenkamp, F. Chiang, W. Chen, and G. R. Gaudette, “Defining the functional border during ischemia using planar deformation and torsion,” (In preparation).

V. S. Patil, C. J. Campbell, Y. H. Yun, S. M. Slack, and D. J. Goetz, “Particle size influences adhesion under flow,” Biophysics Journal, vol. 80(4), p. 1733-1743 (2001).

Y. H. Yun, V. T. Turitto, and J. I. Hochstein, “Porous Media modeling of flow in aneurysms treated with metallic coils,” Proceedings of the 1999 Heat Transfer Conference, HTD99-314, p. 1-11 (1999).

Y. H. Yun, V. T. Turitto, K. P. Daigle, P. Kovacs, J. A. Davidson, and S. M. Slack, “Initial hemocompatibility studies of titanium and zirconium alloys: prekallikrein activation, fibrinogen adsorption, and their correlation withsurface electrochemical properties,” Journal of Biomedical Materials Research, vol. 32, p. 77-85 (1996).

Y. H. Yun, S. M. Slack, K. P. Daigle, J. A. Davidson, and V. T. Turitto, “Initial biocompatibility studies of novel titanium and zirconium alloys for cardiovascular applications,” Compatibility of Biomedical Implants, P. Kovacs and N. S. Istephanous (eds.) vol. 94(15), p. 105-115 (1994).

  Recent Presentations
Y. H. Yun, R. Chan, H. Jiang, and W. Chen, “Microspheres formulated with PEG-grafted-CHN and PLGA exhibit enhanced gene transfection and gene delivery,” Society for Biomaterials, (2004).

Y. H. Yun, A. Kim, M. Frame, D. Checkla, D. Wen, P. Dehazya, and W. Chen, “Modulation of gene transfer by crosslinked hyaluronan,” Hyaluronan, (2003).

E. U. Azeloglu, Y. H. Yun, W. Chen, F. Chiang, I. B Krukenkamp, G. R. Gaudette, “Determination of regional diastolic function in the ischemic heart,” Annals of Biomedical Engineering, (2003).

E. U. Azeloglu, Y. H. Yun, G. R. Gaudette, A. E. Saltman, I. B Krukenkamp, F. Chiang, W. Chen, “Regional mechanical effects of pacing in the intact porcine heart,” 29th Annual Northeast Bioengineering Conference, (2003).

Y. H. Yun, P. B. Yellen, and W. Chen, “Hyaluronic Acid Gene Delivery Microspheres with Sustained Release and Transfection Capabilities,” Annals of Biomedical Engineering, vol. 29, sup. 1, p. S-97 (2001)

D. E. Komatsu,Y. H. Yun, W. Chen, “Characterization of a Novel Film for the Controlled Release of Plasmid DNA,” Annals of Biomedical Engineering, vol. 29, sup. 1, p. S-96 (2001).

Y. H. Yun, S. Raz, Y. Grad, S. Einav, J. Jesty, D. Bluestein, “Platelet procoagulation and DPIV measurements in models of arterial stenosis.” Annals of Biomedical Engineering, vol. 28, sup. 1, p. S-66 (2000).

D. Bluestein, Y. Li,Y. H. Yun, I. B. Krukencamp, J. Jesty, “Free emboli formation and procoagulation properties of platelets induced by flow past mechanical heart valves.” Annals of Biomedical Engineering, vol. 28, sup. 1, p. S-64 (2000).

V. S., Patil, C. Campbell,Y. H. Yun, S. Slack, D. Goetz “Particle diameter influences receptor-ligand mediated adhesion under flow.” Annals of Biomedical Engineering, vol. 28, sup. 1, p. S-88 (2000).

Y. H. Yun, J. I. Hochstein, and V. T. Turitto, “Computational Modeling of Aneurysms treated with metallic coils.” Proceedings of the 1999 National Heat Transfer Conference, (1999).

V. S. Patil, L. Xie, C. J. Campbell, Y. H. Yun, S. M. Slack, and D. G. Goetz, “Particle Deposition in a Parallel Plate Flow Chamber.” The First Joint Meeting of BMES and EMBS, p. 50 (1999).

Y. H. Yun, J. I. Hochstein, and V. T. Turitto, “Computational modeling of an aneurysm filled with porous media.” First Tennessee Biomedical Engineering Conference, (1998).
 
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