601 BIOMEDICAL INSTRUMENTATION I
Analysis of the basics of instrumentation and measurement in biomedical research. Detailed study of instrument calibration procedures. Basic concepts of instrumentation include design criteria and operational analysis, including principles of transduction and signal processing. Practical experience is gained through use of hands-on design, construction and testing of biomedical devices.

611 BIOMETRY
Statistics and experimental design for the biomedical and biomedical engineering disciplines including: distributions, hypothesis testing and estimation, ANOVA, probit analysis and nonparametric statistics.

640 SPINE MECHANICS
Physical properties and functional biomechanics of the spine. Kinematics and kinetics of the human spine. Biomechanics of scoliosis, trauma, instability, pain and orthoses. Mechanics and design of surgical implants.

641 SOFT CONNECTIVE TISSUE BIOMECHANICS / 642 HARD CONNECTIVE TISSUE BIOMECHANICS
Physical properties and functional biomechanics of bone. The biology and mechanics of fracture and fracture healing. Mechanics of external and internal fixators. Total joint implants and reconstruction techniques.

644 MUSCLE MECHANICS AND OPTIMIZATION
Three-dimensional human joint forces and moments, body segment moments of inertia. Muscle mechanics and physiology, including optimization methods used in the solution of muscle forces. Equipment used to study human body kinetics, such as EMG and force plates, will be studied through use of interactive labs.

645 MECHANICS IN PHYSIOLOGY AND MEDICINE
Rheology of blood and body fluids, mechanics of blood and lymph circulation, kinetics and kinematics of orthopaedic joints, impact biomechanics, clinical applications.

647 KINEMATICS OF THE HUMAN BODY
Analytical techniques used to quantify the three-dimensional motion of the segments and joints of the human body, including least squares, Euler angles, helical axis and center of rotation. Experimental methods used to collect kinematic data will be studied through use of interactive labs.

650 CARDIOVASCULAR DYNAMICS
Analysis of blood pumping action, pressure/flow waveform transmission and blood rheology factors. Use of modeling and direct measurement techniques. Clinical implications of disease.

651 CARDIOVASCULAR DIAGNOSTIC AND THERAPEUTICS TECHNIQUES
Cardiovascular disease conditions, instrumentation and techniques for diagnosis and surgical procedures and services for treatment. Direct interaction with active clinical laboratories.

653 TRANSPORT PHENOMENA IN BIOLOGY AND MEDICINE
Basic definitions, cardiovascular mass and Physical properties and functional biomechanics of ligament, tendon, joint capsule insertions, myotendinous junction, articular cartilage and meniscus. The mechanics of injury, repair and replacement for accelerated repair and improved function.

655 REHABILITATION ENGINEERING
Devices for rehabilitation, interfacing the motor or sensory impaired, communication aids, quantitative assessment techniques, prosthetics and orthotics, bedsore mechanics, functional neuromuscular stimulation, emerging technologies, job modification.

660 BIOMATERIALS AND LABORATORY
Material uses in biological applications. Effect of physiological environment and sterilization on materials. Controlled and uncontrolled degradation. Effect of materials on soft tissue, hard tissue and blood. Laboratory experiments using materials designed for biomedical use and demonstration of biological/materials interaction.

663 MEDICAL DEVICES AND ARTIFICIAL ORGANS
Design of medical devices and artificial organs, requirements, safety considerations, tissue constraints, optimization, reliability, government regulations and legal liability. Intensive care, cardiovascular, neuromuscular, surgical, neonatal and prosthetic devices. Laparascopic instruments.

670 MATHEMATICAL MODELING IN BIOLOGY AND MEDICINE
Modeling of pharmacokinetic, neuromuscular cardiovascular and immune systems, and artificial organ interactions. Stochastic and deterministic approaches. Fractal analysis.

697 ST: FINITE ELEMENTS IN BIOMECHANICS
Finite element analysis and its application to problems in biomechanics. Modeling considerations, boundary conditions and loading of physiological systems. Hands-on experience with finite element software.

697 ST: FUNCTIONAL ANATOMY
The anatomy of the musculoskeletal and nervous systems as they relate to the function of movement of the human body. Bones, muscles, joints and nerves will be intensively studied through lecture and dissection labs.

620 NEURAL NETWORKS
Examination of highly parallel, distributed architectures for computing that are derived from structures observed in biological nervous systems. After an overview of how real neurons operate, the course will examine both classical and modern neural computing architectures. Comparisons will be made with traditional serial machines and applications for which neural networks seem most promising.

621 SENSORY SYSTEMS ANALYSIS
Study of various sensory modalities from a systems engineering perspective. Techniques from linear and nonlinear systems analysis are applied to aspects of vision, hearing, touch and position sensing in humans. Comparisons are made with artificial emulations of these sensations.

630 BIOMEDICAL COMPUTING
Computer applications in biomedical research. The course includes a review of contemporary computing tools including symbolic processors, graphics techniques, A/D and D/A conversion, database and spreadsheet use, and peripherals and interface design. The course concludes with an in-depth study of various computer languages used to solve specific biomedical problems.

632 BIOMEDICAL SIGNAL PROCESSING
Applied approach to measurement and analysis of biological continuous signals and point processes, including sampling, Fourier and principal component analysis, correlograms, filters and data displays. Techniques for handling quasiperiodic data and extremely large data sets.

633 DIAGNOSTIC IMAGING TECHNIQUES I
Physics of medical imaging, signal acquisition and image reconstruction for imaging modalities using radioactive energy sources such as X-ray, CT, gamma cameras, PET and electrical impedance tomography.

633 DIAGNOSTIC IMAGING TECHNIQUES II
Physics of medical imaging, signal acquisition, image reconstruction and imaging artifacts for modalities using non-radioactive energy sources such as ultrasound and MRI.

634 MEDICAL IMAGING DEVICES
Engineering and physical aspects of medical imaging devices, including digital X-ray, CT, nuclear medicine devices, ultrasound and MRI.

637 DESIGN, ANALYSIS AND APPLICATIONS OF IMAGING DETECTORS AND BIOSENSORS
Detection and sensing principles, scientific evaluation and development of a strong knowledge of medical imaging detectors and biosensors.

638 IMAGE PROCESSING FOR BIOMEDICAL DATA
Perception and image quality, image sampling, quantization, transforms, data compression, enhancement, restoration, registration and segmentation techniques, projection reconstruction and techniques for the display of 3D data sets.

639 BIOMEDICAL OPTICS AND IMAGING
Principles of modern biomedical lightware imaging science and technology, development of new non-invasive or minimally invasive diagnostic techniques and treatment.

697 ST: HUMAN INTERFACE TECHNOLOGY
Reliability and human error, human information processing, sensory input and perception, display of information, controls and controlling actions, sensors and transducers, virtual reality and associated technologies, teleoperators and telepresence.

Graduate Curriculum